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Off the top of my head, CJ Cherryh's Morgaine saga (female mage, male assistant), three or four books, no romance. (removing this per @what's comment below) ETA so wow, it turned out to be a lot h...
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#4: Attribution notice removed
Source: https://writers.stackexchange.com/a/18837 License name: CC BY-SA 3.0 License URL: https://creativecommons.org/licenses/by-sa/3.0/
#3: Attribution notice added
Source: https://writers.stackexchange.com/a/18837 License name: CC BY-SA 3.0 License URL: https://creativecommons.org/licenses/by-sa/3.0/
#2: Initial revision
Off the top of my head, CJ Cherryh's [Morgaine saga](http://rads.stackoverflow.com/amzn/click/0886778778) (female mage, male assistant), three or four books, no romance. _(removing this per @what's comment below)_ ETA so wow, it turned out to be a _lot_ harder than I thought it was to find examples. Almost every story I can think of at the moment has either two people of the same gender, one gay protagonist, or two straights who eventually end up together. In the Harry Potter series, Harry is the main protagonist of the Big Three, and while Ron and Hermione end up together, and Harry ends up with Ginny, Harry and Hermione remain just friends throughout. In Mercedes Lackey's [_The Silver Gryphon,_](http://rads.stackoverflow.com/amzn/click/0886776856) the third in the Mage Wars trilogy, the two working partners are Tad (a male gryphon) and Blade (a female human); they are friends but there's no romance.