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You say you maybe want your MC to leave the world and his friends. This is no problem and can make for a satisfying ending. Just look at LOTR. I also remember a different Story where the MC basical...
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Source: https://writers.stackexchange.com/a/37997 License name: CC BY-SA 3.0 License URL: https://creativecommons.org/licenses/by-sa/3.0/
#2: Initial revision
You say you maybe want your MC to leave the world and his friends. This is no problem and can make for a satisfying ending. Just look at LOTR. I also remember a different Story where the MC basically becomes a God at the end of the Story after/while he saves the world. You could say he is leaving his old world/life behind, but he still lives a happy life with his mortal love for the rest of her natural life, and then he lives a happy life with his other love who is very long lived. So these endings felt satisfying, and they have something in common: The sidecharacters live a long and happy life until they die a natural death because of age. Maybe they have some problems to overcome (dealing with the political aftermath of the war, rebuilding, uniting everyone), but in general they are now capable of it and succeed. The happy and successful sidecharacters might even balance out the fact that the MC got a bittersweet ending. So I would recommend against killing them. I would also recommend against making the Mc regret leaving. Make it bittersweet (for the reader). (Obviously you can make everything work, but it would definitly go against expectations. And if you want to go against genre expectations, make sure to make it clear from the beginning of the book that this isn't your typical story)