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Andrew Sullivan's Dish (fka The Daily Dish) is about as mixed-topic a professional blog as I can imagine, and it does staggeringly well. The core may be politics, but there are a lot of other ideas...
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#4: Attribution notice removed
Source: https://writers.stackexchange.com/a/3017 License name: CC BY-SA 3.0 License URL: https://creativecommons.org/licenses/by-sa/3.0/
#3: Attribution notice added
Source: https://writers.stackexchange.com/a/3017 License name: CC BY-SA 3.0 License URL: https://creativecommons.org/licenses/by-sa/3.0/
#2: Initial revision
[Andrew Sullivan's Dish](http://andrewsullivan.thedailybeast.com/) (fka The Daily Dish) is about as mixed-topic a professional blog as I can imagine, and it does staggeringly well. The core may be politics, but there are a _lot_ of other ideas covered as well. Smaller business blogs would benefit from focus. Once you get a decent steady readership, you could try widening the topics and see how readers respond, and use that as a guide to whether or how you should expand.