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Starting with a story or event(s) that directly affect the protagonist would make the reader sympathize for the protagonist and every action they take. If you mean to put in an element later on in...
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#3: Attribution notice added
Source: https://writers.stackexchange.com/a/44739 License name: CC BY-SA 3.0 License URL: https://creativecommons.org/licenses/by-sa/3.0/
#2: Initial revision
Starting with a story or event(s) that directly affect the protagonist would make the reader sympathize for the protagonist and every action they take. If you mean to put in an element later on in the story that would be more bizarre, I would suggest you introduce the homicide in the later stages and not in the beginning. Again, if it were a movie, starting with the murder would surely be captivating but I wouldn't care much about the protagonist or in fact every other person involved in the crime scene. Rather, the action happening would definitely be something that would catch my attention. Getting an audience into the protagonist requires some context and a backstory. This is what I feel :)