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Human beings are complex and flawed creatures. We do not each have just the one flaw. We have multiple failings, and multiple lies we tell ourselves. Now, for a story one has to simplify reality so...
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#4: Attribution notice removed
Source: https://writers.stackexchange.com/a/48178 License name: CC BY-SA 4.0 License URL: https://creativecommons.org/licenses/by-sa/4.0/
#3: Attribution notice added
Source: https://writers.stackexchange.com/a/48178 License name: CC BY-SA 4.0 License URL: https://creativecommons.org/licenses/by-sa/4.0/
#2: Initial revision
Human beings are complex and flawed creatures. We do not each have just the one flaw. We have multiple failings, and multiple lies we tell ourselves. Now, for a story one has to simplify reality somewhat - focus only on those lies and flaws that are conductive to telling the story. But if you simplify the story to the point of each character just having the one flaw, you've simplified your characters to the point that they're flat and made of cardboard. Take a simple story: _Othello_. Othello is jealous, that's part of the story. There's a lie he's been told - that's another part. And there's an insecurity in him about his position as a stranger - Iago can play on this insecurity to fuel Othello's jealousy. And even then, it takes a certain mindset to proceed from jealousy to murdering your wife. Take a different simple story: _Harry Potter_. Harry isn't very smart. His inability to think before acting is repeatedly used by Voldemort, in addition to landing him into trouble without Voldemort's involvement. In addition to that, Harry is rash, rather lazy, and that's before we add into the mix the misunderstandings and the lies from other characters. Complex characters are interesting characters. Don't think of your characters as checklists of traits - think of them as people, with multiple strengths and weaknesses.